Developmental delays related to Leigh syndrome may occur earlier than...
Researchers from the Mitochondrial Medicine Frontier Program at Children's Hospital of Philadelphia have found that developmental delays associated with Leigh syndrome, the most common pediatric...
View ArticleStudy finds microglia to be responsible for neuronal death in a mitochondrial...
Microglia, a type of central nervous system cell, is primarily responsible for neuronal death in Leigh Syndrome and the neurological symptoms related to this mitochondrial disease.
View ArticleParents become drug developers to save their children’s lives
Maggie Carmichael wasn't developing like other kids. As a toddler, she wasn't walking and had a limited vocabulary for her age.
View ArticleTwo new zebrafish models for studying the most common cause of Leigh syndrome...
Researchers from Children's Hospital of Philadelphia (CHOP) developed two new zebrafish models for studying a specific genetic form of mitochondrial disease that represents the most common cause of...
View ArticleResearch reveals molecular features of rare mtDNA mutations
A high-throughput single-cell single-mitochondrial genome sequencing technology known as iMiGseq has provided new insights into mutations of mitochondrial DNA (mtDNA) and offers a platform for...
View ArticleCure Mito Foundation releases the first-of-its-kind online resource about...
The Cure Mito Foundation, a parent-led organization dedicated to advancing research and treatments for Leigh syndrome, has launched the first-of-its-kind online resource about Leigh syndrome, the most...
View ArticleCoRDS and Cure MITO join forces with C-Path to advance research for rare...
Critical Path Institute announced today that the Coordination of Rare Diseases based at Sanford Research (CoRDS), in partnership with Cure MITO, will contribute its mitochondrial disorders data from...
View ArticleHope for PDCD and Cure Mito Foundation unveil joint patient registry
Cure Mito Foundation and Hope for PDCD foundation, both patient-led foundations focused on advancing research and supporting families affected by Leigh syndrome and Pyruvate Dehydrogenase Complex...
View ArticleResearchers uncover mechanism behind mitochondrial dysfunction in Alzheimer's
A team of researchers at Johannes Gutenberg University Mainz (JGU) has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of...
View ArticleCannabidiol shown to extend lifespan and improve symptoms in Leigh syndrome...
A study led by the UAB Institut de Neurociències and published in the journal Nature Communications demonstrates in animal models how daily administration of cannabidiol (CBD), a substance obtained...
View ArticleNew drug mimics low-oxygen treatment for Leigh Syndrome
For the average person, living at high altitude-where oxygen is sparser than at sea level-can have health benefits ranging from lower rates of heart disease to increased endurance.
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